Immunophenotyping in presumed ocular histoplasmosis like retinopathy

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Presumed Ocular Histoplasmosis III

Histoplasmin skin tests and dilated funduscopic examination for presumed ocular histoplasmosis were carried out on 842 individuals, aged 13 years and older, from Walkersville, Md. Seventy percent of the male and 51% of the female population were sensitive to the histoplasmin skin test; among reactors, males had a mean diameter of induration of 11.6 mm, and females had a mean induration of 9.7 m...

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De novo lesions in presumed ocular histoplasmosis-like syndrome.

Two patients with multifocal choroiditis similar or identical to POHS are presented. Colour photographs and fluorescein angiography document the occurrence of de novo lesions in the originally involved eye. The cases also demonstrate the development of new choroidal lesions within the originally involved eye, the early evolution of the "basic choroidal lesion", and the need for fluorescein angi...

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Peripapillary neovascular membranes in presumed ocular histoplasmosis.

We studied 39 eyes with ocular histoplasmosis and peripapillary neovascular membranes for an average of 12 months. On the basis of clinical findings, 19 were selected for treatment with photocoagulation. Of the treated eyes, 12 (63%) had a visual result of 6/12 (20/40) or better. Of the 20 untreated eyes, six were clinically untreatable and 14 were electively followed up. All but one of the eye...

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Presumed ocular histoplasmosis in The Netherlands--an area without histoplasmosis.

AIMS/BACKGROUND The syndrome of ocular histoplasmosis is usually prefaced by "presumed' as the aetiology is not yet clear. The aim of this study was to evaluate the clinical features of a similar ocular syndrome in the Netherlands where the fungus Histoplasma capsulatum is not endemic. METHODS A retrospective multicentre study in which all patients were included who were diagnosed with a synd...

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MICA association with presumed ocular histoplasmosis syndrome (POHS).

PURPOSE MHC class I chain related gene A (MICA), a polymorphic and stress-inducible cell surface molecule, is located centromeric to human leukocyte antigen locus B (HLA-B) in the human leukocyte antigen (HLA) region on chromosome 6. MICA is thought to be involved in the innate immune response. An alanine repeat polymorphism is present in the MICA transmembrane region, for which several disease...

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ژورنال

عنوان ژورنال: Eye

سال: 1995

ISSN: 0950-222X,1476-5454

DOI: 10.1038/eye.1995.8